Pesquisa | BVS IEC

1.

Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.

Gray, Zach H; Chakraborty, Damayanti; Duttweiler, Reuben R; Alekbaeva, Gulnaz D; Murphy, Sedona E; Chetal, Kashish; Ji, Fei; Ferman, Benjamin I; Honer, Madison A; Wang, Zhentian; Myers, Cynthia; Sun, Renhong; Kaniskan, H Ümit; Toma, Monika Maria; Bondarenko, Elena A; Santoro, John N; Miranda, Christopher; Dillingham, Megan E; Tang, Ran; Gozani, Or; Jin, Jian; Skorski, Tomasz; Duy, Cihangir; Lee, Hayan; Sadreyev, Ruslan I; Whetstine, Johnathan R.

Cell ; 186(21): 4528-4545.e18, 2023 10 12.

Artigo em Inglês | MEDLINE | ID: mdl-37788669

2.

A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia.

Voit, Richard A; Tao, Liming; Yu, Fulong; Cato, Liam D; Cohen, Blake; Fleming, Travis J; Antoszewski, Mateusz; Liao, Xiaotian; Fiorini, Claudia; Nandakumar, Satish K; Wahlster, Lara; Teichert, Kristian; Regev, Aviv; Sankaran, Vijay G.

Nat Immunol ; 24(1): 69-83, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36522544

3.

The transcription factor LRF promotes integrin ß7 expression by and gut homing of CD8αα⁺ intraepithelial lymphocyte precursors.

Nie, Jia; Carpenter, Andrea C; Chopp, Laura B; Chen, Ting; Balmaceno-Criss, Mariah; Ciucci, Thomas; Xiao, Qi; Kelly, Michael C; McGavern, Dorian B; Belkaid, Yasmine; Bosselut, Rémy.

Nat Immunol ; 23(4): 594-604, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35354951

4.

Beginning of a New Era: Mapping the Bone Marrow Niche.

Nakamura-Ishizu, Ayako; MacArthur, Ben D; Suda, Toshio.

Cell ; 177(7): 1679-1681, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31199915

5.

Evolving as a Scientist and a Mentor.

Cell ; 177(3): 510-513, 2019 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-30952444

6.

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.

Triana, Sergio; Vonficht, Dominik; Jopp-Saile, Lea; Raffel, Simon; Lutz, Raphael; Leonce, Daniel; Antes, Magdalena; Hernández-Malmierca, Pablo; Ordoñez-Rueda, Diana; Ramasz, Beáta; Boch, Tobias; Jann, Johann-Christoph; Nowak, Daniel; Hofmann, Wolf-Karsten; Müller-Tidow, Carsten; Hübschmann, Daniel; Alexandrov, Theodore; Benes, Vladimir; Trumpp, Andreas; Paulsen, Malte; Velten, Lars; Haas, Simon.

Nat Immunol ; 22(12): 1577-1589, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34811546

7.

Mechanisms that promote and suppress chromosomal translocations in lymphocytes.

Gostissa, Monica; Alt, Frederick W; Chiarle, Roberto.

Annu Rev Immunol ; 29: 319-50, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21219174

8.

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m⁶A/MYC/CEBPA Signaling.

Su, Rui; Dong, Lei; Li, Chenying; Nachtergaele, Sigrid; Wunderlich, Mark; Qing, Ying; Deng, Xiaolan; Wang, Yungui; Weng, Xiaocheng; Hu, Chao; Yu, Mengxia; Skibbe, Jennifer; Dai, Qing; Zou, Dongling; Wu, Tong; Yu, Kangkang; Weng, Hengyou; Huang, Huilin; Ferchen, Kyle; Qin, Xi; Zhang, Bin; Qi, Jun; Sasaki, Atsuo T; Plas, David R; Bradner, James E; Wei, Minjie; Marcucci, Guido; Jiang, Xi; Mulloy, James C; Jin, Jie; He, Chuan; Chen, Jianjun.

Cell ; 172(1-2): 90-105.e23, 2018 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-29249359

9.

Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.

Isoda, Takeshi; Moore, Amanda J; He, Zhaoren; Chandra, Vivek; Aida, Masatoshi; Denholtz, Matthew; Piet van Hamburg, Jan; Fisch, Kathleen M; Chang, Aaron N; Fahl, Shawn P; Wiest, David L; Murre, Cornelis.

Cell ; 171(1): 103-119.e18, 2017 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-28938112

10.

A Time Bomb for Leukemia.

Maryanovich, Maria; Frenette, Paul S.

Cell ; 165(2): 262-3, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27058656

11.

Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.

Guarnerio, Jlenia; Bezzi, Marco; Jeong, Jong Cheol; Paffenholz, Stella V; Berry, Kelsey; Naldini, Matteo M; Lo-Coco, Francesco; Tay, Yvonne; Beck, Andrew H; Pandolfi, Pier Paolo.

Cell ; 165(2): 289-302, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27040497

12.

CircR-looping the leukemic translocations: The cause of MLL translocations explained.

Chen, Mo.

Mol Cell ; 83(13): 2164-2166, 2023 Jul 06.

Artigo em Inglês | MEDLINE | ID: mdl-37419090

13.

SRSF2 plays an unexpected role as reader of m⁵C on mRNA, linking epitranscriptomics to cancer.

Ma, Hai-Li; Bizet, Martin; Soares Da Costa, Christelle; Murisier, Frédéric; de Bony, Eric James; Wang, Meng-Ke; Yoshimi, Akihide; Lin, Kuan-Ting; Riching, Kristin M; Wang, Xing; Beckman, John I; Arya, Shailee; Droin, Nathalie; Calonne, Emilie; Hassabi, Bouchra; Zhang, Qing-Yang; Li, Ang; Putmans, Pascale; Malbec, Lionel; Hubert, Céline; Lan, Jie; Mies, Frédérique; Yang, Ying; Solary, Eric; Daniels, Danette L; Gupta, Yogesh K; Deplus, Rachel; Abdel-Wahab, Omar; Yang, Yun-Gui; Fuks, François.

Mol Cell ; 83(23): 4239-4254.e10, 2023 Dec 07.

Artigo em Inglês | MEDLINE | ID: mdl-38065062

14.

m⁶A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis.

Ciesla, Maciej; Ngoc, Phuong Cao Thi; Muthukumar, Sowndarya; Todisco, Gabriele; Madej, Magdalena; Fritz, Helena; Dimitriou, Marios; Incarnato, Danny; Hellström-Lindberg, Eva; Bellodi, Cristian.

Mol Cell ; 83(7): 1165-1179.e11, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-36944332

15.

Transcription factor networks link B-lymphocyte development and malignant transformation in leukemia.

Sigvardsson, Mikael.

Genes Dev ; 37(15-16): 703-723, 2023 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-37673459

16.

Splice it up: Atypical transcripts to boost leukemia immunotherapy.

Cieri, Nicoletta; Wu, Catherine J.

Immunity ; 54(4): 608-610, 2021 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-33852826

17.

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams.

Metzger, Michael J; Reinisch, Carol; Sherry, James; Goff, Stephen P.

Cell ; 161(2): 255-63, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25860608

18.

MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape.

Olsen, Sarah Naomi; Godfrey, Laura; Healy, James P; Choi, Yoolim A; Kai, Yan; Hatton, Charles; Perner, Florian; Haarer, Elena L; Nabet, Behnam; Yuan, Guo-Cheng; Armstrong, Scott A.

Mol Cell ; 82(6): 1140-1155.e11, 2022 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-35245435

19.

Supramolecular assembly of GSK3α as a cellular response to amino acid starvation.

Hinze, Laura; Schreek, Sabine; Zeug, Andre; Ibrahim, Nurul Khalida; Fehlhaber, Beate; Loxha, Lorent; Cinar, Buesra; Ponimaskin, Evgeni; Degar, James; McGuckin, Connor; Chiosis, Gabriela; Eckert, Cornelia; Cario, Gunnar; Bornhauser, Beat; Bourquin, Jean-Pierre; Stanulla, Martin; Gutierrez, Alejandro.

Mol Cell ; 82(15): 2858-2870.e8, 2022 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-35732190

20.

Structural basis for product specificities of MLL family methyltransferases.

Li, Yanjing; Zhao, Lijie; Zhang, Yuebin; Wu, Ping; Xu, Ying; Mencius, Jun; Zheng, Yongxin; Wang, Xiaoman; Xu, Wancheng; Huang, Naizhe; Ye, Xianwen; Lei, Ming; Shi, Pan; Tian, Changlin; Peng, Chao; Li, Guohui; Liu, Zhijun; Quan, Shu; Chen, Yong.

Mol Cell ; 82(20): 3810-3825.e8, 2022 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-36108631

BVS IEC

Instituto Evandro Chagas

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